德谷胰岛素是一种超长效胰岛素,活性类似于内源性人胰岛素,用于治疗1型和2型糖尿病引起的高血糖。德谷胰岛素B链经酰化修饰并切除一个末尾苏氨酸后,在生理pH值下具有活性,其作用持续时间被显著延长至42小时。
本品由能高效表达德谷胰岛素的大肠杆菌菌株经发酵而来,纯度高,内毒素含量极低,且不含任何动物源性病原体。
Insulin degludec is an ultra-long-acting insulin with activity similar to that of endogenous human insulin and is used to treat hyperglycemia caused by type 1 and type 2 diabetes. After acylation of the B-chain and removal of a terminal threonine, insulin degludec is active at physiological pH and its duration of action is significantly prolonged to 42 hours.
Virtu Pharmako utilizes E. coli strains to produce insulin degludec. It has extremely low endotoxin content with high purity,and does not contain any animal-derived pathogens.